Mavacamten Using this medicine with any of the subsequent medicines is generally not recommended, but may be demanded sometimes. If both medicines are prescribed alongside one another, your doctor may alter the dose or how often you utilize just one or each with the medicines.
danazol will boost the degree or influence of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Mysterious.
Whereas modafinil and armodafinil are approved for narcolepsy, they are actually repurposed as adjunctive solutions to alleviate indications of acute depressive stage in those with bipolar dysfunction.[58] Drug repurposing in psychiatry is a method for locating new makes use of for medicine which have presently been authorized or analyzed in medical trials for other sicknesses. As a result, drug repurposing is usually a quick, Price tag-helpful, and reduced-threat approach for the event of latest treatment options for psychiatric Issues.
nefazodone will increase the amount or influence of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
When a physician prescribes modafinil, they supply specific Recommendations on dosages for their unique use.
Indicated to enhance wakefulness in adults with too much sleepiness linked to shift work disorder (SWD)
sparsentan will minimize the level or impact of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and decreases efficacy connected with these substrates.
Intrauterine progress restriction and spontaneous abortion happen to be noted with modafinil and armodafinil
A number of people prefer to consider their modafinil in smaller doses. This produces the weakest consequences at first, nonetheless it’s the safest option for lengthy-term use.
Efficacy and safety of adjunctive modafinil remedy on residual extreme daytime sleepiness between nasal continual optimistic airway stress-taken care of japanese people with obstructive sleep apnea syndrome: a double-blind placebo-controlled study.
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efavirenz will reduce the level or outcome of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
cenobamate will increase the level or effect of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep track of Closely. Think about a dose reduction check it out here of CYP2C19 substrates, as clinically suitable, when utilized concomitantly with cenobamate.